Ken‐ichi Matsumura

Structure−Activity Relationships of a Novel Class of Endothelin-A Receptor Antagonists and Discovery of Potent and Selective Receptor Antagonist, 2-(Benzo[1,3]dioxol-5-yl)-6-isopropyloxy-4-(4-methoxyphenyl)-2<i>H</i>-chromene-3- carboxylic Acid (S-1255). 1. Study on Structure−Activity Relationships and Basic Structure Crucial for ET_A Antagonism

Natsuki Ishizuka, Ken‐ichi Matsumura, Katsunori Sakai et al. · Journal of Medicinal Chemistry · 2002 · 80 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Dissociative charge-transfer reactions of Ar+ with simple aliphatic hydrocarbons at thermal energy

Masaharu Tsuji, Hiroyuki Kouno, Ken‐ichi Matsumura et al. · The Journal of Chemical Physics · 1993 · 67 citations

Natural Sciences, Chemistry, Chemical Kinetics +14

An Efficient Method for the Preparation of Enantiomerically Pure N-Acylarylsulfonamides Having an Asymmetric Center at the α-Position: Condensation of Acid Chlorides and Arylsulfonamides Under Solid-Liquid Two-Phase Conditions

Natsuki Ishizuka, Ken‐ichi Matsumura, Kunio Hayashi et al. · Synthesis · 2000 · 29 citations

Pharmacy, Chemistry, Medicinal Chemistry +9

Practical Enantioselective Synthesis of Endothelin Antagonist S-1255 by Dynamic Resolution of 4-Methoxychromene-3-carboxylic Acid Intermediate

Toshiro Konoike, Ken‐ichi Matsumura, Tadahiko Yorifuji et al. · The Journal of Organic Chemistry · 2002 · 20 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Identification of novel indole derivatives as highly potent AMPK activators with anti-diabetic profiles

Yuusuke Tamura, Ippei Morita, Yu Hinata et al. · Bioorganic & Medicinal Chemistry Letters · 2022 · 11 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +16