Concepedia
Statistics
Publications
15
Citations
1.9K
H-Index
Active since
2008
Affiliations
Seagen (United States)(Current)
University of Washington
The University of Western Australia
University of Tasmania
James Cook University
Joshua H. Hunter is an author at Seagen (United States) specializing in medicine, pharmacology, and antibody engineering.
Top concepts
MedicinePharmacologyAntibody EngineeringImmunologyNatural SciencesImmunotherapyDrug DiscoveryMedicinal ChemistryBiochemistryBiomolecular Engineering
Publications per year
2008–2023
Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index
Robert P. Lyon, Tim D. Bovee, Svetlana O. Doronina et al. · Nature Biotechnology · 2015 · 498 citations
Medicinal Chemistry, Polymer-drug Conjugate, Medicine +8
Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates
Robert P. Lyon, Jocelyn R. Setter, Tim D. Bovee et al. · Nature Biotechnology · 2014 · 430 citations
Pharmaceutical Science, Biochemistry, Polymer-drug Conjugate +9
A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology
Scott C. Jeffrey, Patrick Burke, Robert P. Lyon et al. · Bioconjugate Chemistry · 2013 · 241 citations
Drug Target, Immunology, Molecular Biology +21
Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody–Drug Conjugates
Patrick Burke, Joseph Z. Hamilton, Scott C. Jeffrey et al. · Molecular Cancer Therapeutics · 2016 · 142 citations
Orthogonal Cysteine Protection Enables Homogeneous Multi‐Drug Antibody–Drug Conjugates
Matthew R. Levengood, Xinqun Zhang, Joshua H. Hunter et al. · Angewandte Chemie International Edition · 2016 · 131 citations · Full text
1–5 of 15