Concepedia
Statistics
Publications
29
Citations
2.5K
H-Index
20
Active since
2000
Affiliations
Seagen (United States)(Current)
University of Colorado Boulder
Washington University in St. Louis
University of Colorado Denver
University of Colorado Cancer Center
Patrick Burke is an author at Seagen (United States) specializing in medicine, pharmacology, and drug discovery.
Top concepts
MedicinePharmacologyDrug DiscoveryBiochemistryNatural SciencesMedicinal ChemistryAntibody EngineeringBiomolecular EngineeringMusicMusicology
Publications per year
2000–2020
Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index
Robert P. Lyon, Tim D. Bovee, Svetlana O. Doronina et al. · Nature Biotechnology · 2015 · 498 citations
Medicinal Chemistry, Polymer-drug Conjugate, Medicine +8
SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML
May S.K. Sutherland, Roland B. Walter, Scott C. Jeffrey et al. · Blood · 2013 · 381 citations
A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology
Scott C. Jeffrey, Patrick Burke, Robert P. Lyon et al. · Bioconjugate Chemistry · 2013 · 241 citations
Drug Target, Immunology, Molecular Biology +21
Development of orally active inhibitors of protein and cellular fucosylation
Nicole M. Okeley, Stephen C. Alley, Martha E. Anderson et al. · Proceedings of the National Academy of Sciences · 2013 · 183 citations · Full text
Vitro Fucosylation, Glycobiology, Immunology +21
Formaldehyde in Human Cancer Cells: Detection by Preconcentration-Chemical Ionization Mass Spectrometry
Shuji Kato, Patrick Burke, Tad H. Koch et al. · Analytical Chemistry · 2001 · 157 citations
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