Concepedia
Statistics
Publications
30
Citations
2.5K
H-Index
20
Active since
2000
Affiliations
Seagen (United States)(Current)
University of Colorado Boulder
Washington University in St. Louis
University of Colorado Denver
University of Colorado Cancer Center
Patrick Burke is an author at Seagen (United States) specializing in pharmacy, antibody conjugates, and antibody-drug conjugates.
Publications per year
2000–2021
Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index
Robert P. Lyon, Tim D. Bovee, Svetlana O. Doronina et al. · Nature Biotechnology · 2015 · 523 citations
Pharmacy, Pharmaceutics, Pharmacokinetics +14
SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML
May S.K. Sutherland, Roland B. Walter, Scott C. Jeffrey et al. · Blood · 2013 · 386 citations
Pharmacy, Oncology, Pharmacology +13
A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology
Scott C. Jeffrey, Patrick Burke, Robert P. Lyon et al. · Bioconjugate Chemistry · 2013 · 246 citations
Pharmacy, Oncology, Pharmacology +17
Development of orally active inhibitors of protein and cellular fucosylation
Nicole M. Okeley, Stephen C. Alley, Martha E. Anderson et al. · Proceedings of the National Academy of Sciences · 2013 · 192 citations · Full text
Medicine, Medicinal Chemistry, Pharmacology +17
Formaldehyde in Human Cancer Cells: Detection by Preconcentration-Chemical Ionization Mass Spectrometry
Shuji Kato, Patrick Burke, Tad H. Koch et al. · Analytical Chemistry · 2001 · 158 citations
Pharmacy, Oncology, Toxicology +14
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