Concepedia

R Bai

RB

6

Publications

643

Citations

6

H-Index

1990

Active since

Affiliations

Arizona State University(Current)

National Cancer Institute

National Institutes of Health

R Bai is an author at Arizona State University specializing in natural sciences, pharmacology, and drug discovery.

Top concepts

PharmacologyNatural SciencesMedicineBiochemistryDrug DiscoveryChemical BiologyMedicinal ChemistryCytoskeletonDrug ResistanceMolecular Biology

Publications per year

1990–1998

6

Publications

6

Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites.

R Bai, George R. Pettit, Ernest Hamel · Journal of Biological Chemistry · 1990 · 285 citations · Full text

Antiparasitic Agent, Distinct Site, Cytoskeleton +19

Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.

R Bai, Zbigniew A. Cichacz, Cherry L. Herald et al. · Molecular Pharmacology · 1993 · 128 citations

Characterization of the interaction of cryptophycin 1 with tubulin: binding in the Vinca domain, competitive inhibition of dolastatin 10 binding, and an unusual aggregation reaction.

R Bai, Robert E. Schwartz, John A. Kepler et al. · PubMed · 1996 · 74 citations

Purified Tubulin, Molecular Biology, Cellular Pharmacology +19

Antineoplastic agents 337. Synthesis of dolastatin 10 structural modifications.

George R. Pettit, Jayaram K. Srirangam, József Barkóczy et al. · PubMed · 1995 · 70 citations

Peptide Engineering, Molecular Biology, Cytoskeleton +16

Antineoplastic agents 365. Dolastatin 10 SAR probes.

G.R. Pettit, Jayaram K. Srirangam, József Barkóczy et al. · PubMed · 1998 · 64 citations

Bioorganic Chemistry, Sar Probes, Pharmaceutical Chemistry +16

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