Lakshman Bindu

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation

Timothy H. Tran, Albert H. Chan, Lucy C. Young et al. · Nature Communications · 2021 · 239 citations · Full text

Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ

Srisathiyanarayanan Dharmaiah, Lakshman Bindu, Timothy H. Tran et al. · Proceedings of the National Academy of Sciences · 2016 · 170 citations · Full text

Comparative analysis of 10 small molecules binding to carbonic anhydrase II by different investigators using Biacore technology

Giuseppe A. Papalia, Stephanie A. Leavitt, Maggie A. Bynum et al. · Analytical Biochemistry · 2006 · 116 citations

Bioorganic Chemistry, Engineering, Biochemistry +10

Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory Circuit

Daniel A. Ritt, Maria Teresa Abreu‐Blanco, Lakshman Bindu et al. · Molecular Cell · 2016 · 98 citations · Full text

Reductive Stress, Signal Transduction, Signaling Pathway +9

Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions

William Gillette, Dominic Esposito, Maria Abreu Blanco et al. · Scientific Reports · 2015 · 79 citations · Full text