Lakshman Bindu - Concepedia

Concepedia

Author

Lakshman Bindu

Frederick National Laboratory for Cancer Research

Also Known As

Bindu L., Lakshman Bindu, Lakshman K. Bindu, Lakshman?K. Bindu

39

Publications

1.2K

Citations

16

H-Index

41

Concepts

All Affiliations

Frederick National Laboratory for Cancer Research Science Applications International Corporation (United States)National Institutes of Health National Cancer Institute Center for Cancer Research

LB

About

Lakshman Bindu is an author at Frederick National Laboratory for Cancer Research specializing in medicine, natural sciences, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	288
2	Natural Sciences	10	10	339
3	Biochemistry	9	9	268
4	Engineering	1	1	116
5	Biomolecular Engineering	1	1	44

Lakshman Bindu

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23

Publications

1.2K

Citations

16

H-Index

	Year	Citations
KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation Timothy H. Tran, Albert H. Chan, Lucy C. Young, Nature Communications	2021	239
Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ Srisathiyanarayanan Dharmaiah, Lakshman Bindu, Timothy H. Tran, Proceedings of the National Academy of Sciences	2016	170
Comparative analysis of 10 small molecules binding to carbonic anhydrase II by different investigators using Biacore technology Giuseppe A. Papalia, Stephanie A. Leavitt, Maggie A. Bynum, Analytical Biochemistry Bioorganic ChemistryEngineeringBiochemistryNatural SciencesBiomolecular Analysis	2006	116
Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory Circuit Daniel A. Ritt, Maria Teresa Abreu‐Blanco, Lakshman Bindu, Molecular Cell Reductive StressSignal TransductionSignaling PathwayReceptor Tyrosine KinaseRas/raf/mek/erk Pathway Signaling	2016	98
Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions William Gillette, Dominic Esposito, Maria Abreu Blanco, Scientific Reports	2015	79
Synthesis and Biological Evaluation of Indenoisoquinolines That Inhibit Both Tyrosyl-DNA Phosphodiesterase I (Tdp1) and Topoisomerase I (Top1) Martin Conda‐Sheridan, P. Venkat Reddy, Andrew Morrell, Journal of Medicinal Chemistry	2012	69
KRAS Prenylation Is Required for Bivalent Binding with Calmodulin in a Nucleotide-Independent Manner Constance Agamasu, Rodolfo Ghirlando, Troy Taylor, Biophysical Journal	2019	53
PDE6D Inhibitors with a New Design Principle Selectively Block K-Ras Activity Farid Ahmad Siddiqui, Catharina Alam, Petja Rosenqvist, ACS Omega Molecular DockingCombinatorial ChemistryMedicinal ChemistryChaperone Pde6dDrug Target	2019	44
Application of azide–alkyne cycloaddition ‘click chemistry’ for the synthesis of Grb2 SH2 domain-binding macrocycles Won Jun Choi, Zhendan Shi, Karen M. Worthy, Bioorganic & Medicinal Chemistry Letters HeterocyclicBiochemistryNatural SciencesOrganic ChemistryClick Chemistry	2006	43
The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling Marco Biancucci, G. Minasov, Avik Banerjee, Science Signaling	2018	40

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