Albert H. Chan

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation

Timothy H. Tran, Albert H. Chan, Lucy C. Young et al. · Nature Communications · 2021 · 239 citations · Full text

Discovery and structure–activity relationship analysis of Staphylococcus aureus sortase A inhibitors

Nuttee Suree, Sung Wook Yi, William Thieu et al. · Bioorganic & Medicinal Chemistry · 2009 · 104 citations · Full text

Inhibitory Activity, Antimicrobial Drug Discovery, Biochemistry +8

Discovery of <i><scp>S</scp>taphylococcus aureus</i> Sortase <scp>A</scp> Inhibitors Using Virtual Screening and the Relaxed Complex Scheme

Albert H. Chan, Jeff Wereszczynski, Brendan R. Amer et al. · Chemical Biology & Drug Design · 2013 · 57 citations · Full text

Drug Target, Hit Identification, Staphylococcus Aureus +19

Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography

Albert H. Chan, Won‐Gil Lee, Krasimir A. Spasov et al. · Proceedings of the National Academy of Sciences · 2017 · 49 citations · Full text

Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C

Anna E. Maciag, James P. Stice, Bin Wang et al. · Cancer Discovery · 2024 · 33 citations · Full text

Molecular Biology, Direct Target Coverage, Adaptive Resistance +19