Timothy H. Tran

Engineering and characterization of a superfolder green fluorescent protein

J.D. Pédelacq, Stéphanie Cabantous, Timothy H. Tran et al. · Nature Biotechnology · 2005 · 2.5K citations

Life Sciences, Biochemistry, Molecular Biology +12

Multivalent Small-Molecule Pan-RAS Inhibitors

Matthew Welsch, Anna Kaplan, Jennifer M. Chambers et al. · Cell · 2017 · 283 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation

Timothy H. Tran, Albert H. Chan, Lucy C. Young et al. · Nature Communications · 2021 · 252 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

G. Aaron Hobbs, Nicole M. Baker, Anne M. Miermont et al. · Cancer Discovery · 2019 · 226 citations · Full text

Medicine, Genetics, Oncology +12

Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ

Srisathiyanarayanan Dharmaiah, Lakshman Bindu, Timothy H. Tran et al. · Proceedings of the National Academy of Sciences · 2016 · 176 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17