Brain-Targeted Proanthocyanidin Metabolites for Alzheimer's Disease Treatment

Jun Wang, Mário G. Ferruzzi, Lap Ho, +19

Journal of Neuroscience

MoMo: discovery of statistically significant post-translational modification motifs

Alice Cheng, Charles E. Grant, William Stafford Noble, +1

Bioinformatics

Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease

Wei Zhao, Merina Varghese, Prashant Vempati, +7

PLoS ONE

Als Spinal CordOxidative StressNeurologyNeuropathologyCaprylic Triglyceride +14

Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

Wei Zhao, Merina Varghese, Shrishailam Yemul, +8

Molecular Neurodegeneration

Heterogeneity in Red Wine Polyphenolic Contents Differentially Influences Alzheimer's Disease-type Neuropathology and Cognitive Deterioration

Lap Ho, Ling Hong Chen, Jun Wang, +11

Journal of Alzheimer s Disease

Targeting multiple pathogenic mechanisms with polyphenols for the treatment of Alzheimer's disease-experimental approach and therapeutic implications

Jun Wang, Weina Bi, Alice Cheng, +10

Frontiers in Aging Neuroscience

Neurochemical BiomarkersTherapeutic ImplicationsDisease-experimental ApproachPolyphenolicsOxidative Stress +16

Role of standardized grape polyphenol preparation as a novel treatment to improve synaptic plasticity through attenuation of features of metabolic syndrome in a mouse model

Jun Wang, Cheuk Y. Tang, Mário G. Ferruzzi, +16

Molecular Nutrition & Food Research

Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor-Mediated Inhibition of T-Type Calcium Channels

Yanjun Zhao, Sivaprakash Sivaji, Michael C. Chiang, +13

Neuron

Signal TransductionMolecular PhysiologyMolecular BiologyNeuropeptide ReceptorT-type Calcium Channels +6

Unintended Effects of Cardiovascular Drugs on the Pathogenesis of Alzheimer’s Disease

Jun Wang, Zhong Zhao, Emi Lin, +10

PLoS ONE

Individual DrugsUnintended EffectsNeurochemical BiomarkersPharmacotherapyAlzheimer ’ +22

Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease

Jun Wang, Mário G. Ferruzzi, Merina Varghese, +6

Molecular Neurodegeneration