Simon Ruedisser

Nuclear Magnetic Resonance of Hyperpolarized Fluorine for Characterization of Protein–Ligand Interactions

Youngbok Lee, Haifeng Zeng, Simon Ruedisser et al. · Journal of the American Chemical Society · 2012 · 92 citations

Hyperpolarized Fluorine, Fluorine Nmr Spectroscopy, Single Molecule Biophysics +14

Fragment-Based Screening by Biochemical Assays: Systematic Feasibility Studies with Trypsin and MMP12

Andreas Boettcher, Simon Ruedisser, P. Erbel et al. · SLAS DISCOVERY · 2010 · 40 citations · Full text

Engineering, Biological Mass Spectrometry, Peptide Science +24

Azaindoles as Zinc‐Binding Small‐Molecule Inhibitors of the JAMM Protease CSN5

Eva Altmann, P. Erbel, Martin Renatus et al. · Angewandte Chemie International Edition · 2016 · 28 citations

Csn5 Inhibitors, Molecular Regulation, Jamm Protease Csn5 +20

Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach

Edwige Lorthiois, James Roache, David Barnes‐Seeman et al. · Journal of Medicinal Chemistry · 2020 · 22 citations · Full text

A Novel Class of Oral Direct Renin Inhibitors: Highly Potent 3,5-Disubstituted Piperidines Bearing a Tricyclic P₃<b>–</b>P₁Pharmacophore

Nils Ostermann, Simon Ruedisser, Claus Ehrhardt et al. · Journal of Medicinal Chemistry · 2013 · 20 citations · Full text