Targeting Glioma Stem Cells by Functional Inhibition of a Prosurvival OncomiR-138 in Malignant Gliomas

Xin Hui Derryn Chan, Srikanth Nama, Felicia E. Gopal, +9

Cell Reports

DLAT subunit of the pyruvate dehydrogenase complex is upregulated in gastric cancer-implications in cancer therapy.

Wen Quan Jonathan Goh, Ghim Siong Ow, Vladimir A. Kuznetsov, +2

PubMed

Metabolic RemodelingTumor BiologyGastrointestinal OncologyCancer Cell BiologyMetabolism +19

EGF hijacks miR-198/FSTL1 wound-healing switch and steers a two-pronged pathway toward metastasis

Gopinath M. Sundaram, Hisyam M. Ismail, Mohsin Bashir, +11

The Journal of Experimental Medicine

Complementary intestinal mucosa and microbiota responses to caloric restriction

Kalina Duszka, Sandrine Ellero‐Simatos, Ghim Siong Ow, +9

Scientific Reports

NutritionDysbiosisHost-microbe InteractionsMicrobiota ResponsesImmunology +22

Genome and transcriptome delineation of two major oncogenic pathways governing invasive ductal breast cancer development

Luay Aswad, Surya Pavan Yenamandra, Ghim Siong Ow, +3

Oncotarget

Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification

Liming Chen, Piroon Jenjaroenpun, Andrea Mun Ching Pillai, +15

Proceedings of the National Academy of Sciences

Big genomics and clinical data analytics strategies for precision cancer prognosis

Ghim Siong Ow, Vladimir A. Kuznetsov

Scientific Reports

Variable SignatureEngineeringMachine LearningBig Data AnalyticsPrognosis +25

Identification of two poorly prognosed ovarian carcinoma subtypes associated with<i>CHEK2</i>germ-line mutation and non-<i>CHEK2</i>somatic mutation gene signatures

Ghim Siong Ow, Anna V. Ivshina, Gloria Fuentes, +1

Cell Cycle

Expression and clinical role of chemoresponse-associated genes in ovarian serous carcinoma

Dag André Nymoen, Thea E. Hetland Falkenthal, Arild Holth, +6

Gynecologic Oncology

Tumor BiologyChemoresponse-associated GenesMedicinePathologyCancer Genomics +8

Sense-antisense gene-pairs in breast cancer and associated pathological pathways

Oleg V. Grinchuk, Efthymios Motakis, Surya Pavan Yenamandra, +6

Oncotarget

Tumor BiologyBreast OncologyFunctional GenomicsMedicineFunctional Genome Architectures +10