RG Melton

A cytotoxic agent can be generated selectively at cancer sites

K D Bagshawe, Springer Cj, F Searle et al. · British Journal of Cancer · 1988 · 265 citations · Full text

Medicine, Cancer Biology, Oncology +11

Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure

Sylvia Buchen, Doris NGampolo, RG Melton et al. · British Journal of Cancer · 2005 · 150 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Regression of established breast carcinoma xenografts with antibody-directed enzyme prodrug therapy against c-erbB2 p185.

Sue Eccles, William Court, Gary Box et al. · PubMed · 1994 · 80 citations

Medicine, Oncology, Pharmacology +17

Polyethylene glycol modification of a galactosylated streptavidin clearing agent: effects on immunogenicity and clearance of a biotinylated anti-tumour antibody

Damian Marshall, RB Pedley, JA Boden et al. · British Journal of Cancer · 1996 · 63 citations · Full text

Pharmacy, Immunology, Oncology +15

ZD2767, an improved system for antibody-directed enzyme prodrug therapy that results in tumor regressions in colorectal tumor xenografts.

D C Blakey, P. J. Burke, D. Huw Davies et al. · PubMed · 1996 · 60 citations

Pharmacy, Oncology, Pharmacology +16