D C Blakey

A phase I trial of antibody directed enzyme prodrug therapy (ADEPT) in patients with advanced colorectal carcinoma or other CEA producing tumours

Roslyn J. Francis, Sanjay Sharma, Caroline J. Springer et al. · British Journal of Cancer · 2002 · 162 citations · Full text

Pharmacy, Oncology, Pharmacology +15

Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A-chain and hindered disulfide linkages.

P E Thorpe, Philip M. Wallace, P.P. Knowles et al. · PubMed · 1988 · 156 citations

Life Sciences, Immunology, Pharmacology +14

A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression

Karel Ulbrich, Vladimír Šubr, Vivien Mautner et al. · Gene Therapy · 2000 · 111 citations

Pharmacy, Genetics, Molecular Biology +16

Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging

Simon P. Robinson, Dominick J. O. McIntyre, D. Checkley et al. · British Journal of Cancer · 2003 · 110 citations · Full text

Medicine, Oncology, Pharmacology +14

Purification of ricin A1, A2, and B chains and characterization of their toxicity.

R J Fulton, D C Blakey, P.P. Knowles et al. · Journal of Biological Chemistry · 1986 · 103 citations · Full text

Pharmacy, Biochemistry, Toxicology +17