Lyne Lévesque

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing

Gang Yu, Masaki Nishimura, Shigeki Arawaka et al. · Nature · 2000 · 904 citations

Signal Transduction, Molecular Physiology, Signaling Pathway +8

The Presenilin 1 Protein Is a Component of a High Molecular Weight Intracellular Complex That Contains β-Catenin

Gang Yu, Fusheng Chen, Georges Lévesque et al. · Journal of Biological Chemistry · 1998 · 369 citations · Full text

Presenilin 1 Controls γ-Secretase Processing of Amyloid Precursor Protein in Pre-Golgi Compartments of Hippocampal Neurons

Wim Annaert, Lyne Lévesque, Katleen Craessaerts et al. · The Journal of Cell Biology · 1999 · 312 citations · Full text

Protein Secretion, Molecular Biology, Amyloid Precursor Protein +19

Phosphorylation, Subcellular Localization, and Membrane Orientation of the Alzheimer's Disease-associated Presenilins

Bart De Strooper, Monique Beullens, Bart Contreras et al. · Journal of Biological Chemistry · 1997 · 289 citations · Full text

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of β-catenin,a component of the presenilin protein complex

Masaki Nishimura, Gang Yu, Georges Lévesque et al. · Nature Medicine · 1999 · 222 citations

Neurodegenerative Diseases, Alzheimer's Disease, Presenilin Mutations +9