Weiguo Zhang

Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2

Ker Yu, Celine Shi, Lourdes Toral‐Barza et al. · Cancer Research · 2010 · 208 citations · Full text

Medicine, Oncology, Pharmacology +14

Mouse TCRαβ+CD8αα Intraepithelial Lymphocytes Express Genes That Down-Regulate Their Antigen Reactivity and Suppress Immune Responses

Timothy L. Denning, Steve W. Granger, Daniel Mucida et al. · The Journal of Immunology · 2007 · 160 citations · Full text

Life Sciences, Cell Biology, Immunology +17

A New Pharmacologic Action of CCI-779 Involves FKBP12-Independent Inhibition of mTOR Kinase Activity and Profound Repression of Global Protein Synthesis

Boris Shor, Weiguo Zhang, Lourdes Toral‐Barza et al. · Cancer Research · 2008 · 120 citations · Full text

Medicine, Oncology, Pharmacology +13

LAT-mediated signaling in CD4+CD25+ regulatory T cell development

Surapong Koonpaew, Shudan Shen, Lawrence O. Flowers et al. · The Journal of Experimental Medicine · 2005 · 116 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Knock-in Mutation of the Distal Four Tyrosines of Linker for Activation of T Cells Blocks Murine T Cell Development

Connie L. Sommers, Rashmi K. Menon, Alexander Grinberg et al. · The Journal of Experimental Medicine · 2001 · 104 citations · Full text

Life Sciences, Immunology, Molecular Biology +17