Pamela Chan

Novel Foxo1-dependent transcriptional programs control Treg cell function

Weiming Ouyang, Will Liao, Chong Luo et al. · Nature · 2012 · 395 citations · Full text

Transcriptional Regulation, Signal Transduction, Treg Cell Function +8

Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice

Jing Qing, Xiangnan Du, Yongmei Chen et al. · Journal of Clinical Investigation · 2009 · 252 citations · Full text

Bladder Carcinoma, Fgf Receptor 3, Genitourinary Cancer +15

Antibody-Drug Conjugates for the Treatment of Non–Hodgkin's Lymphoma: Target and Linker-Drug Selection

Andrew G. Polson, Jill Calemine-Fenaux, Pamela Chan et al. · Cancer Research · 2009 · 247 citations

Immunology, Chemical Linkers, Immunotherapeutics +17

A strategy for risk mitigation of antibodies with fast clearance

Isidro Hötzel, Frank‐Peter Theil, L. Bernstein et al. · mAbs · 2012 · 246 citations · Full text

Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model

William J. Meilandt, Hai Ngu, Alvin Gogineni et al. · Journal of Neuroscience · 2020 · 206 citations · Full text

Synaptic Signaling, Ps2app Alzheimer, Social Sciences +21