Isidro Hötzel

Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing

Ji Li, Nicola J. Stagg, Jennifer Johnston et al. · Cancer Cell · 2017 · 292 citations · Full text

Life Sciences, Immunology, Oncology +17

A strategy for risk mitigation of antibodies with fast clearance

Isidro Hötzel, Frank‐Peter Theil, L. Bernstein et al. · mAbs · 2012 · 247 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals

Rebecca S. LaRue, S. Jönsson, Kevin A.T. Silverstein et al. · BMC Molecular Biology · 2008 · 192 citations · Full text

Life Sciences, Evolutionary Biology, Molecular Biology +17

Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies

Leonard D. Goldstein, Ying-Jiun J. Chen, Jia Wu et al. · Communications Biology · 2019 · 179 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement

Seung-Hye Lee, Claire E. Le Pichon, Oskar Adolfsson et al. · Cell Reports · 2016 · 132 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17