Gerald P. McCafferty

N-((1 S)-1-{[4-((2 S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part I

Kevin S. Thorneloe, Anthony C. Sulpizio, Zuojun Lin et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 404 citations

Medicine, Pharmacology, Physiology +16

Identification of a Selective Nonpeptide Antagonist of the Anaphylatoxin C3a Receptor That Demonstrates Antiinflammatory Activity in Animal Models

Robert S. Ames, Dennis Lee, James J. Foley et al. · The Journal of Immunology · 2001 · 201 citations · Full text

Medicine, Immunology, Pharmacology +17

The discovery of GSK221149A: A potent and selective oxytocin antagonist

John Liddle, Michael Allen, Alan D. Borthwick et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 92 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

GW427353 (Solabegron), a Novel, Selective β3-Adrenergic Receptor Agonist, Evokes Bladder Relaxation and Increases Micturition Reflex Threshold in the Dog

Alexandra Hicks, Gerald P. McCafferty, Erin S. Riedel et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 91 citations

Medicine, Pharmacology, Pharmacotherapy +13

Enhanced bladder capacity and reduced prostaglandin E₂-mediated bladder hyperactivity in EP3 receptor knockout mice

Gerald P. McCafferty, Blake A. Misajet, Nicholas J. Laping et al. · American Journal of Physiology-Renal Physiology · 2008 · 58 citations

Medicine, Pharmacology, Urology +17