Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor

Jared N. Cumming, Elizabeth M. Smith, Lingyan Wang, +19

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetActive Bace1 InhibitorBiochemistryDrug Design +9

A Continuous Spectrophotometric Assay for the Hepatitis C Virus Serine Protease

Rumin Zhang, Brian M. Beyer, James Durkin, +4

Analytical Biochemistry

Diagnostic VirologyBiochemistryViral DiagnosticsViral HepatitisMedicine +7

Disulfide bond assignments and secondary structure analysis of human and murine interleukin 10

William T. Windsor, Rosalinda Syto, Anthony Tsarbopoulos, +6

Biochemistry

Laboratory ImmunologyImmunologyImmune RegulationImmunologic MechanismImmune System +18

Molecular Characterization of the Melanin-Concentrating Hormone/Receptor Complex: Identification of Critical Residues Involved in Binding and Activation

Douglas Macdonald, Nicholas Murgolo, Rumin Zhang, +4

Molecular Pharmacology

Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides

Rumin Zhang, James Durkin, William T. Windsor, +3

Journal of Virology

Protein ChemistryBiochemistryProtein FoldingNatural SciencesSubstrate Specificity +13

Identification of a minimal hydrophobic domain in the herpes simplex virus type 1 scaffolding protein which is required for interaction with the major capsid protein

Zhi Hong, M Beaudet-Miller, James Durkin, +2

Journal of Virology

Viral ReplicationImmunologyMolecular BiologyIcp35 FormsViral Structural Protein +18

Azapeptides as inhibitors of the hepatitis C virus NS3 serine protease

Rumin Zhang, James Durkin, William T. Windsor

Bioorganic & Medicinal Chemistry Letters

MedicineAntiviral Drug DevelopmentAntiviral TherapyHepatitisVirology +6

Enhancement of Hepatitis C Virus NS3 Proteinase Activity by Association with NS4A-Specific Synthetic Peptides: Identification of Sequence and Critical Residues of NS4A for the Cofactor Activity

Nancy Butkiewicz, Michelle Wendel, Rumin Zhang, +10

Virology

BiochemistryNatural SciencesNs4a-specific Synthetic PeptidesHepatitisMolecular Biology +6

<i>ARTEMIA</i>HEMOGLOBINS: GENETIC VARIATION IN PARTHENOGENETIC AND ZYGOGENETIC POPULATIONS

Sarane T. Bowen, James Durkin, Gery Sterling, +1

Biological Bulletin

BiologyGenetic DiversitySan Francisco ShrimpsPhenotypic VariationMolecular Ecology +13

Thermodynamic and Structural Analysis of Phosphotyrosine Polypeptide Binding to Grb2-SH2

Charles McNemar, Mark E. Snow, William T. Windsor, +6

Biochemistry