Douglas Macdonald - Concepedia

Concepedia

Author

Douglas Macdonald

CHDI Foundation ORCID

Also Known As

D MacDonald, D Macdonald, D. MacDonald, D. Macdonald, Douglas M. Macdonald, Douglas Macdonald, Douglas Macdonald (562225)

52

Publications

1.6K

Citations

22

H-Index

78

Concepts

All Affiliations

CHDI Foundation Evotec (Germany)University College London IRBM Science Park Charles River Laboratories (Netherlands)

DM

About

Douglas Macdonald is an author at CHDI Foundation specializing in medicine, natural sciences, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	576
2	Natural Sciences	8	8	406
3	Engineering	2	2	51
4	Business	1	1	16
5	Management	1	1	16

Douglas Macdonald

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30

Publications

1.6K

Citations

22

H-Index

	Year	Citations
Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients Edward J. Wild, Roberto Boggio, Douglas R. Langbehn, Journal of Clinical Investigation	2015	258
Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression Andreas Weiss, Ulrike Träger, Edward J. Wild, Journal of Clinical Investigation ImmunologyImmune RegulationCell DeathImmunotherapyImmune System	2012	146
Position 9 replacement analogs of glucagon uncouple biological activity and receptor binding. Cecilia G. Unson, Douglas Macdonald, Kerry Ray, Journal of Biological Chemistry GlycobiologyPharmacotherapyExperimental PharmacologyCellular PhysiologyMolecular Pharmacology	1991	90
Molecular Characterization of the Melanin-Concentrating Hormone/Receptor Complex: Identification of Critical Residues Involved in Binding and Activation Douglas Macdonald, Nicholas Murgolo, Rumin Zhang, Molecular Pharmacology	2000	87
SCH-202676: An Allosteric Modulator of Both Agonist and Antagonist Binding to G Protein-Coupled Receptors Ahmad Fawzi, Douglas Macdonald, Lawrence L. Benbow, Molecular Pharmacology	2001	80
A Profiling Platform for the Characterization of Transglutaminase 2 (TG2) Inhibitors Sabine Schaertl, Michael E. Prime, John Wityak, SLAS DISCOVERY	2010	74
Discovery and Structure–Activity Relationship of Potent and Selective Covalent Inhibitors of Transglutaminase 2 for Huntington’s Disease Michael E. Prime, Ole A. Andersen, John J. Barker, Journal of Medicinal Chemistry Structure–activity RelationshipBiochemistryG Protein-coupled ReceptorMedicineTg2 Inhibitors	2012	69
Quantification Assays for Total and Polyglutamine-Expanded Huntingtin Proteins Douglas Macdonald, Michela Tessari, Ivette Boogaard, PLoS ONE Knockout MouseProtein FunctionProtein ExpressionHuntingtin ProteinNatural Sciences	2014	63
Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay Valentina Fodale, Roberto Boggio, Manuel Daldin, Journal of Huntington s Disease	2017	60
Synthesis and SAR of novel 4,5-diarylimidazolines as potent P2X7 receptor antagonists Gregory H. Merriman, Liang Ma, Patrick Shum, Bioorganic & Medicinal Chemistry Letters Novel 4,5-DiarylimidazolinesMedicinal ChemistryDrug TargetBiochemistryMedicine	2004	55

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