Neil R. Hartman

In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-Dideoxyinosine

Robert Yarchoan, Hiroaki Mitsuya, Rose V. Thomas et al. · Science · 1989 · 425 citations

Medicine, Infectious Diseases, Pharmacology +17

Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.

Carlo Federico Perno, Robert Yarchoan, David A. Cooney et al. · The Journal of Experimental Medicine · 1989 · 290 citations · Full text

Life Sciences, Immunology, Microbiology +14

Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.

Carlo Federico Perno, Robert Yarchoan, David A. Cooney et al. · The Journal of Experimental Medicine · 1988 · 232 citations · Full text

Medicine, Infectious Diseases, Pharmacology +17

Factors determining the activity of 2',3'-dideoxynucleosides in suppressing human immunodeficiency virus in vitro.

David A. Cooney, Neil R. Hartman, Carlo Federico Perno et al. · Molecular Pharmacology · 1988 · 160 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation

Andrés M. Rubiano, Amruta Indapurkar, Ryosuke Yokosawa et al. · Clinical and Translational Science · 2020 · 93 citations · Full text

Pharmacy, Pharmacology, Toxicology +17