Neil R. Hartman

In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-Dideoxyinosine

Robert Yarchoan, Hiroaki Mitsuya, Rose V. Thomas et al. · Science · 1989 · 425 citations

Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.

Carlo Federico Perno, Robert Yarchoan, David A. Cooney et al. · The Journal of Experimental Medicine · 1989 · 290 citations · Full text

Human Immunodeficiency Virus, Viral Production, Related Congeners +15

Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.

Carlo Federico Perno, Robert Yarchoan, David A. Cooney et al. · The Journal of Experimental Medicine · 1988 · 232 citations · Full text

Several Dideoxynucleosides, Human Immunodeficiency Virus, Medicine +14

Factors determining the activity of 2',3'-dideoxynucleosides in suppressing human immunodeficiency virus in vitro.

David A. Cooney, Neil R. Hartman, Carlo Federico Perno et al. · Molecular Pharmacology · 1988 · 160 citations

Pharmacokinetics of 2′, 3′-dideoxyadenosine and 2′, 3′-dideoxyinosine in patients with severe human immunodeficiency virus infection

Neil R. Hartman, Robert Yarchoan, James M. Pluda et al. · Clinical Pharmacology & Therapeutics · 1990 · 133 citations

Therapeutic Drug Monitoring, Plasma Kinetics, Drug Infusion +14