Francis Ince

From ATP to AZD6140: The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis

Brian Springthorpe, A. S. Bailey, Patrick Barton et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 235 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

QSAR and the Rational Design of Long-Acting Dual D₂-Receptor/β₂-Adrenoceptor Agonists

Rupert P. Austin, Patrick Barton, Roger V. Bonnert et al. · Journal of Medicinal Chemistry · 2003 · 65 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Dual D₂-Receptor and β₂-Adrenoceptor Agonists for the Treatment of Airway Diseases. 1. Discovery and Biological Evaluation of Some 7-(2-Aminoethyl)- 4-hydroxybenzothiazol-2(3<i>H</i>)-one Analogues

Roger V. Bonnert, Roger C. Brown, David A. Chapman et al. · Journal of Medicinal Chemistry · 1998 · 51 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Novel Cobalt Complex Inhibitors of Mitochondrial Calcium Uptake

John Unitt, Kerry L Boden, A.V. Wallace et al. · Bioorganic & Medicinal Chemistry · 1999 · 22 citations

Life Sciences, Biochemistry, Cell Biology +13

A Mild and Convenient High-Yield Alternative to the Protic Acid Catalysed Pictet-Spengler Synthesis of Tetrahydroisoquinolines

Gi K. Cheung, Martyn J. Earle, Robin A. Fairhurst et al. · Synlett · 1991 · 16 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10