A.V. Wallace

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

Elsa D. Garcin, A.S. Arvai, R.J. Rosenfeld et al. · Nature Chemical Biology · 2008 · 264 citations · Full text

Anchored Plasticity, Engineering, Biochemistry +11

Insulin and glucagon regulate the activation of two distinct membrane-bound cyclic AMP phosphodiesterases in hepatocytes

C M Heyworth, A.V. Wallace, Miles D. Houslay · Biochemical Journal · 1983 · 157 citations · Full text

1,2-Dihydro-4-quinazolinamines:  Potent, Highly Selective Inhibitors of Inducible Nitric Oxide Synthase Which Show Antiinflammatory Activity in Vivo

Alan C. Tinker, Haydn G. Beaton, N. K. Boughton-Smith et al. · Journal of Medicinal Chemistry · 2003 · 95 citations · Full text

Highly Selective Inhibitors, Medicinal Chemistry, Bioorganic Chemistry +15

Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles:  Crystallographic and Computational Analyses of Inhibitor Potency

R.J. Rosenfeld, Elsa D. Garcin, Koustubh Panda et al. · Biochemistry · 2002 · 72 citations

Bioorganic Chemistry, Nitric Oxide, Molecular Biology +18

Hit-to-Lead studies: The discovery of potent, orally bioavailable thiazolopyrimidine CXCR2 receptor antagonists

Andrew Baxter, Anne Cooper, Elizabeth Kinchin et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 54 citations · Full text

Drug Target, Biochemistry, Medicine +9