Elizabeth Kinchin

Discovery of Potent and Selective Adamantane-Based Small-Molecule P2X₇Receptor Antagonists/Interleukin-1β Inhibitors

Mark Furber, Lilian Alcaraz, Janice Bent et al. · Journal of Medicinal Chemistry · 2007 · 58 citations · Full text

Rat P2x7 Receptor, Immunology, Pharmacotherapy +16

Hit-to-Lead studies: The discovery of potent, orally bioavailable thiazolopyrimidine CXCR2 receptor antagonists

Andrew Baxter, Anne Cooper, Elizabeth Kinchin et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 54 citations · Full text

Drug Target, Biochemistry, Medicine +9

Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate

Mark Furber, A.K. Tiden, Philip Gardiner et al. · Journal of Medicinal Chemistry · 2014 · 54 citations · Full text

Drug Target, Cathepsin C Inhibitors, Lead Identification +17

Dual D₂-Receptor and β₂-Adrenoceptor Agonists for the Treatment of Airway Diseases. 1. Discovery and Biological Evaluation of Some 7-(2-Aminoethyl)- 4-hydroxybenzothiazol-2(3<i>H</i>)-one Analogues

Roger V. Bonnert, Roger C. Brown, David A. Chapman et al. · Journal of Medicinal Chemistry · 1998 · 51 citations

Molecular Pharmacology, Inflammatory Lung Disease, Biochemistry +15

Hit-to-Lead studies: The discovery of potent, orally bioavailable triazolethiol CXCR2 receptor antagonists

Andrew Baxter, Colin Bennion, Janice Bent et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 46 citations · Full text

Pharmaceutical Science, Drug Target, Pharmacology +7