Alan C. Tinker

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

Elsa D. Garcin, A.S. Arvai, R.J. Rosenfeld et al. · Nature Chemical Biology · 2008 · 264 citations · Full text

Anchored Plasticity, Engineering, Biochemistry +11

1,2-Dihydro-4-quinazolinamines:  Potent, Highly Selective Inhibitors of Inducible Nitric Oxide Synthase Which Show Antiinflammatory Activity in Vivo

Alan C. Tinker, Haydn G. Beaton, N. K. Boughton-Smith et al. · Journal of Medicinal Chemistry · 2003 · 95 citations · Full text

Highly Selective Inhibitors, Medicinal Chemistry, Bioorganic Chemistry +15

2-Aminopyridines as Highly Selective Inducible Nitric Oxide Synthase Inhibitors. Differential Binding Modes Dependent on Nitrogen Substitution

Stephen Connolly, Anders Åberg, A.S. Arvai et al. · Journal of Medicinal Chemistry · 2004 · 42 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, 4-Piperidine Carbamate +15

3,4-Dihydro-1-isoquinolinamines: A novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency

Haydn G. Beaton, Peter Hamley, David Nicholls et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 38 citations · Full text

Medicinal Chemistry, Biochemistry, Reactive Nitrogen Specie +9

Electrophilic substitution in indoles. Part 15. The reaction between methylenedi-indoles and p-nitrobenzenediazonium fluoroborate

Anthony H. Jackson, Noojaree Prasitpan, P. V. R. SHANNON et al. · Journal of the Chemical Society Perkin Transactions 1 · 1987 · 31 citations

High Yields, P-nitrobenzenediazonium Fluoroborate, Engineering +11