Peter Hamley

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

Elsa D. Garcin, A.S. Arvai, R.J. Rosenfeld et al. · Nature Chemical Biology · 2008 · 270 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

1,2-Dihydro-4-quinazolinamines:  Potent, Highly Selective Inhibitors of Inducible Nitric Oxide Synthase Which Show Antiinflammatory Activity in Vivo

Alan C. Tinker, Haydn G. Beaton, N. K. Boughton-Smith et al. · Journal of Medicinal Chemistry · 2003 · 96 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms

Qi Wu, Ai-Ling Tian, Bei Li et al. · Journal for ImmunoTherapy of Cancer · 2021 · 77 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Spirocycle assembly through selective tandem ring closing metathesis reactions

Martin J. Bassindale, Peter Hamley, Andreas Leitner et al. · Tetrahedron Letters · 1999 · 73 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

2-Aminopyridines as Highly Selective Inducible Nitric Oxide Synthase Inhibitors. Differential Binding Modes Dependent on Nitrogen Substitution

Stephen Connolly, Anders Åberg, A.S. Arvai et al. · Journal of Medicinal Chemistry · 2004 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10