Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals

Masahiko Izumikawa, Ryosei Minoda, Kohei Kawamoto, +5

Nature Medicine

GeneticsAudiologyGenetic EngineeringAtoh1 Gene TherapyAuditory Physiology +12

The Coxsackievirus-Adenovirus Receptor Protein Can Function as a Cellular Attachment Protein for Adenovirus Serotypes from Subgroups A, C, D, E, and F

Peter W. Roelvink, Alena Lizonová, Jennifer G. M. Lee, +6

Journal of Virology

Ad SerotypesVirus StructureDifferent SubgroupsMolecular VirologyCoxsackievirus-adenovirus Receptor Protein +12

<i>Math1</i>Gene Transfer Generates New Cochlear Hair Cells in Mature Guinea Pigs<i>In Vivo</i>

Kohei Kawamoto, Shin-ichi Ishimoto, Ryosei Minoda, +2

Journal of Neuroscience

GeneticsMolecular GeneticsCellular PhysiologyMath1 Gene InsertMath1 Protein +20

Pigment epithelium‐derived factor inhibits retinal and choroidal neovascularization

Keisuke Mori, Elia J. Duh, Peter Gehlbach, +10

Journal of Cellular Physiology

Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

Thomas J. Wickham, Peter W. Roelvink, Douglas E. Brough, +1

Nature Biotechnology

Cell TypesHeparan-containing ReceptorsGene Delivery EfficiencyMolecular BiologyVirology +7

Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen

Toshikazu Kurihara, Douglas E. Brough, Imre Kovesdi, +1

Journal of Clinical Investigation

Tumor XenograftsViral ReplicationImmunologyReplication-competent AdenovirusCancer Biology +15

Vestibular Hair Cell Regeneration and Restoration of Balance Function Induced by Math1 Gene Transfer

Hinrich Staecker, Mark Praetorius, Kim Baker, +1

Otology & Neurotology

Construction of a Pseudoreceptor That Mediates Transduction by Adenoviruses Expressing a Ligand in Fiber or Penton Base

David A. Einfeld, Douglas E. Brough, Peter W. Roelvink, +2

Journal of Virology

TNFerade Biologic: Preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene

Henrik Rasmussen, Camilla Rasmussen, Maria Lempicki, +4

Cancer Gene Therapy

Tumor BiologyOncogenic AgentPathologyRadiation-inducible PromoterRadiopharmaceutical Therapy +5

Novel adenovirus vaccine vectors based on the enteric-tropic serotype 41

Franck Lemiale, Hédi Haddada, Gary J. Nabel, +3

Vaccine

VaccinationImmunologyVirologyVaccine DesignMedicine +2