Paul Leff - Concepedia

Author

Paul Leff

Loughborough University

Also Known As

Bond, Richard A., Burnstock, Geoffrey, P Leff, P. Leff, PAUL LEFF, Paul LEFF, Paul Leff

Publications

3.4K

Citations

H-Index

Concepts

All Affiliations

Loughborough University St Mary's Hospital

About

Paul Leff is an author at Loughborough University specializing in medicine, pharmacology, and physiology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	12	1.7K
2	Biochemistry	4	4	635
3	Engineering	2	2	266
4	Natural Sciences	1	1	35
5	Biomolecular Engineering	1	1	82

Paul Leff

Publications

2.5K

Citations

H-Index

Page 1

	Year	Citations
Effector Pathway-Dependent Relative Efficacy at Serotonin Type 2A and 2C Receptors: Evidence for Agonist-Directed Trafficking of Receptor Stimulus Kelly A. Berg, Saul Maayani, Joseph Goldfarb, Molecular Pharmacology	1998	512
The two-state model of receptor activation Paul Leff Trends in Pharmacological Sciences Signal TransductionG Protein-coupled ReceptorFunctional SelectivityPhysiologyReceptor (Biochemistry)	1995	504
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor Richard A. Bond, Paul Leff, T. David Johnson, Nature Molecular PharmacologyCardiac MuscleMolecular PhysiologyMedicineInverse Agonists	1995	420
Antagonists of the Platelet P<i><sub>2T</sub></i> Receptor: A Novel Approach to Antithrombotic Therapy Anthony H. Ingall, John Dixon, Andrew Bailey, Journal of Medicinal Chemistry Antithrombotic TherapyNovel ApproachPharmacotherapyPlatelet AggregationThrombosis	1999	285
From ATP to AZD6140: The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis Brian Springthorpe, A. S. Bailey, Patrick Barton, Bioorganic & Medicinal Chemistry Letters ThrombosisPlatelet Aggregation InhibitorsBiochemistryBlood PlateletMedicine	2007	233
Further concerns over Cheng-Prusoff analysis Paul Leff, Iain G. Dougall Trends in Pharmacological Sciences Spectral TheoryEngineeringFourier AnalysisCheng-prusoff AnalysisPoisson Boundary	1993	184
Deviations from Michaelis-Menten kinetics. The possibility of complicated curves for simple kinetic schemes and the computer fitting of experimental data for acetylcholinesterase, acid phosphatase, adenosine deaminase, arylsulphatase, benzylamine oxidase, chymotrypsin, fumarase, galactose dehydrogenase, β-galactosidase, lactate dehydrogenase, peroxidase and xanthine oxidase William G. Bardsley, Paul Leff, J. P. Kavanagh, Biochemical Journal EngineeringMolecular BiologyMichaelis-menten KineticsEnzymatic ModificationRedox Biology	1980	82
Inverse agonism: theory and practice Paul Leff Trends in Pharmacological Sciences Philosophical InquiryInverse Agonism	1995	80
A three-state receptor model of agonist action Paul Leff, Clare Scaramellini, Clare Law, Trends in Pharmacological Sciences Molecular PharmacologySignal TransductionFunctional SelectivityMedicinePhysiology	1997	59
Steady-state kinetic studies of the negative co-operativity and flip-flop mechanism for <i>Escherichia coli</i> alkaline phosphatase Roy D. Waight, Paul Leff, William G. Bardsley Biochemical Journal Biophysical ModelingAnalytical UltracentrifugationNegative Co-operativityBioenergeticsBioanalysis	1977	35

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