Patrick K. Clark - Concepedia

Author

Patrick K. Clark

Science Applications International Corporation (United States)

Also Known As

P K Clark, P. K. Clark, P.K. CLARK, P.K. Clark, PATRICK CLARK, Patrick Clark, Patrick K Clark, Patrick K. CLARK, Patrick K. Clark

Publications

2.1K

Citations

H-Index

Concepts

All Affiliations

Science Applications International Corporation (United States)Frederick National Laboratory for Cancer Research National Cancer Institute Rutgers, The State University of New Jersey National Institutes of Health

About

Patrick K. Clark is an author at Science Applications International Corporation (United States) specializing in medicine, molecular biology, and hiv.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	17	1.3K
2	Natural Sciences	13	14	932
3	Biochemistry	7	7	464
4	Biomolecular Engineering	4	4	268
5	Engineering	1	1	66

Patrick K. Clark

Publications

Citations

H-Index

Page 1

	Year	Citations
Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants Kalyan Das, Arthur D. Clark, Paul Lewi, Journal of Medicinal Chemistry	2004	511
Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations Alfredo Jacobo‐Molina, Raymond G. Nanni, Roger Williams, Nature Virus StructureViral ReplicationViral Polymerase StructureNatural SciencesHuman Retrovirus	1992	187
Crystal Structures of 8-Cl and 9-Cl TIBO Complexed with Wild-type HIV-1 RT and 8-Cl TIBO Complexed with the Tyr181Cys HIV-1 RT Drug-resistant Mutant Kalyan Das, Jianping Ding, Y. Hsiou, Journal of Molecular Biology Wild-type Hiv-1 RtBiochemistry9-Cl Tibo ComplexedNatural SciencesHuman Retrovirus	1996	187
Structures of HIV-1 RT–DNA complexes before and after incorporation of the anti-AIDS drug tenofovir Steve Tuske, Stefan G. Sarafianos, Arthur D. Clark, Nature Structural & Molecular Biology Natural SciencesHuman RetrovirusImmunologyHiv-1 Rt–dna ComplexesDna Replication	2004	161
HIV-1 Reverse Transcriptase Structure with RNase H Inhibitor Dihydroxy Benzoyl Naphthyl Hydrazone Bound at a Novel Site D.M. Himmel, Stefan G. Sarafianos, Sanjeewa Dharmasena, ACS Chemical Biology Viral ReplicationViral Polymerase StructureNovel SiteMolecular BiologyAntiviral Drug	2006	141
Conformation of the HIV-1 Gag Protein in Solution Siddhartha A.K. Datta, Joseph E. Curtis, William Ratcliff, Journal of Molecular Biology Virus StructureProtein FoldingMolecular BiologyConformational StudyHiv-1 Gag Protein	2006	141
Interactions between HIV-1 Gag Molecules in Solution: An Inositol Phosphate-mediated Switch Siddhartha A.K. Datta, Zhuojun Zhao, Patrick K. Clark, Journal of Molecular Biology Human RetrovirusImmunologyAntiviral ResponseMolecular BiologyVirology	2006	137
HIV-1 Reverse Transcriptase Purified from a Recombinant Strain of <i>Escherichia coli</i> Patrick K. Clark, Andrea L. Ferris, D.A. Miller, AIDS Research and Human Retroviruses	1990	71
Why Do HIV-1 and HIV-2 Use Different Pathways to Develop AZT Resistance? Paul L. Boyer, Stefan G. Sarafianos, Patrick K. Clark, PLoS Pathogens EngineeringHiv-1 ResistanceImmunologyMolecular BiologyAntiviral Drug	2006	66
HIV-1 and HIV-2 Reverse Transcriptases: Different Mechanisms of Resistance to Nucleoside Reverse Transcriptase Inhibitors Paul L. Boyer, Patrick K. Clark, Stephen H. Hughes Journal of Virology ImmunologyMolecular BiologyAntiviral DrugChemical BiologyDrug Resistance	2012	47

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