In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Carlos Garcı́a-Echeverrı́a, Mark Pearson, Andreas Marti, +15

Cancer Cell

Cancer ResearchMedicineReceptor Tyrosine KinaseVivo Antitumor ActivityNvp-aew541—a Novel +7

New Aza-Dipeptide Analogues as Potent and Orally Absorbed HIV-1 Protease Inhibitors:  Candidates for Clinical Development

Guido Bold, Alexander Fässler, Hans‐Georg Capraro, +18

Journal of Medicinal Chemistry

ImmunologyPharmacotherapyAntiviral DrugCgp 75176Pharmaceutical Chemistry +15

Biological effects of modified colchicines. Improved preparation of 2-demethylcolchicine, 3-demethylcolchicine, and (+)-colchicine and reassignment of the position of the double bond in dehydro-7-deacetamidocolchicines

M. ROESNER, Hans‐Georg Capraro, Arthur E. Jacobson, +6

Journal of Medicinal Chemistry

2,6,9-trisubstituted purines : Optimization towards highly potent and selective CDK1 inhibitors

Patricia Imbach, Hans‐Georg Capraro, Pascal Furet, +3

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistrySelective Cdk1 Inhibitors2,6,9-Trisubstituted PurinesBiochemistryOptimization Towards +11

Aza-Peptide Analogs as Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors with Oral Bioavailability

Alexander Fässler, Guido Bold, Hans‐Georg Capraro, +6

Journal of Medicinal Chemistry

Oral BioavailabilityBioorganic ChemistryImmunologyPharmacotherapyAntiviral Drug +17

Pharmacokinetics and Body Distribution of Liposomal Zinc Phthalocyanine in Tumor‐Bearing Mice: Influence of Aggregation State, Particle Size, and Composition

Ute Isele, Klaus Schieweck, Reinhard Kessler, +2

Journal of Pharmaceutical Sciences

NanomedicineLiposomal Zinc PhthalocyanineBody DistributionPharmacologyRadiation Oncology +1

Large‐Scale Production of Liposomes Containing Monomeric Zinc Phthalocyanine by Controlled Dilution of Organic Solvents

Ute Isele, Peter van Hoogevest, Rolf Hilfiker, +3

Journal of Pharmaceutical Sciences

Lipid PreparationLarge‐scale ProductionOrganic SolventsEngineeringBiotechnology +3

Structure-based design of potent CDK1 inhibitors derived from olomoucine

Pascal Furet, Juerg Zimmermann, Hans‐Georg Capraro, +2

Journal of Computer-Aided Molecular Design

<title>CGP 55 847, liposome-delivered zinc(II)-phthalocyanine as a phototherapeutic agent for tumors</title>

Klaus Schieweck, Hans‐Georg Capraro, Ute Isele, +3

Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

NanomedicineMedicinal ChemistryPhototherapeutic AgentPhotodynamic TherapyLiposome-delivered Zinc +12

¹³C‐ and ¹H‐NMR. Assignments for colchicine derivatives

Charles D. Hufford, Hans‐Georg Capraro, Arnold Brossi

Helvetica Chimica Acta

Derivative (Chemistry)BiochemistryMagnetic Resonance SpectroscopyNatural SciencesMolecular Biology +10