Patricia Imbach

Ethnobotanical-Directed Discovery of the Antihyperglycemic Properties of Cryptolepine: Its Isolation from <i>Cryptolepis</i> <i>sanguinolenta</i>, Synthesis, and in Vitro and in Vivo Activities

Donald Bierer, Diana M. Fort, Christopher D. Mendez et al. · Journal of Medicinal Chemistry · 1998 · 133 citations

The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis

Georg Martiny‐Baron, Philipp Holzer, Éric Billy et al. · Angiogenesis · 2010 · 124 citations · Full text

Antihyperglycemic Activities of Cryptolepine Analogues:  An Ethnobotanical Lead Structure Isolated from<i>Cryptolepis sanguinolenta</i>

Donald Bierer, L. G. DUBENKO, Pingsheng Zhang et al. · Journal of Medicinal Chemistry · 1998 · 104 citations

2,6,9-trisubstituted purines : Optimization towards highly potent and selective CDK1 inhibitors

Patricia Imbach, Hans‐Georg Capraro, Pascal Furet et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 81 citations · Full text

Medicinal Chemistry, Selective Cdk1 Inhibitors, 2,6,9-Trisubstituted Purines +13

DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance

Martin Schröder, Martin Renatus, Xiaoyou Liang et al. · Nature Communications · 2024 · 71 citations · Full text