Immunomodulatory and antioxidant potential of <i>Lactobacillus</i> exopolysaccharides

Chin-Feng Liu, Kuo-Chuan Tseng, Shen-Shih Chiang, +3

Journal of the Science of Food and Agriculture

Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice

Wei-Hsuan Hsu, Ting-Hung Chen, Bao-Hong Lee, +2

Food and Chemical Toxicology

InflammationMetabolic SyndromeMedicineLiver PhysiologyPhysiology +8

Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo

Bao-Hong Lee, Wei-Hsuan Hsu, Yu-Ying Chang, +3

Free Radical Biology and Medicine

InflammationMetabolic SyndromeRedox SignalingDiabetes ManagementBiochemistry +10

Antihypertensive Effects of Lactobacillus-Fermented Milk Orally Administered to Spontaneously Hypertensive Rats

Chin Feng Liu, Yi Ting Tung, Cheng Wu, +3

Journal of Agricultural and Food Chemistry

NutritionHypertensionBlood PressureAntihypertensive EffectsProbiotic +15

Monascus-fermented metabolite monascin suppresses inflammation via PPAR-γ regulation and JNK inactivation in THP-1 monocytes

Wei-Hsuan Hsu, Bao-Hong Lee, Te-Han Liao, +2

Food and Chemical Toxicology

InflammationCytokineAnti-inflammatoryBiochemistryMonascus-fermented Metabolite Monascin +8

The Monascus metabolite monascin against TNF-α-induced insulin resistance via suppressing PPAR-γ phosphorylation in C2C12 myotubes

Bao-Hong Lee, Wei-Hsuan Hsu, Te-Han Liao, +1

Food and Chemical Toxicology

Metabolic SyndromeInsulin SignalingEnergy MetabolismSignal TransductionMolecular Physiology +12

A novel natural Nrf2 activator with PPARγ-agonist (monascin) attenuates the toxicity of methylglyoxal and hyperglycemia

Wei-Hsuan Hsu, Bao-Hong Lee, Yu-Ying Chang, +2

Toxicology and Applied Pharmacology

Redox SignalingMetabolic SyndromeBiochemistryMedicinePhysiology +7

Dimerumic acid attenuates receptor for advanced glycation endproducts signal to inhibit inflammation and diabetes mediated by Nrf2 activation and promotes methylglyoxal metabolism into d-lactic acid

Bao-Hong Lee, Wei-Hsuan Hsu, Ya-Wen Hsu, +1

Free Radical Biology and Medicine

InflammationMetabolic SyndromeBiochemistryMedicineLipid Peroxidation +8

Effects of Monascin on Anti-inflammation Mediated by Nrf2 Activation in Advanced Glycation End Product-Treated THP-1 Monocytes and Methylglyoxal-Treated Wistar Rats

Bao-Hong Lee, Wei-Hsuan Hsu, Tao Huang, +3

Journal of Agricultural and Food Chemistry

Lipid PeroxidationImmunologyRetinoic AcidCell DeathMonascin Administration Group +19

Monascin Attenuates Oxidative Stress-Mediated Lung Inflammation via Peroxisome Proliferator-Activated Receptor-Gamma (PPAR-γ) and Nuclear Factor-Erythroid 2 Related Factor 2 (Nrf-2) Modulation

Wei-Hsuan Hsu, Bao-Hong Lee, Tzu‐Ming Pan

Journal of Agricultural and Food Chemistry

Acute Lung InjuryInflammatory Lung DiseaseOxidative Stress PathwayLung InflammationImmunology +15