Mary Jeanne Kallman

Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740):  A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties

James A. Monn, Matthew J. Valli, Steven M. Massey et al. · Journal of Medicinal Chemistry · 1997 · 392 citations

Pharmacological Characterization, Active Group 2, Psychotropic Medication +16

Anxiolytic and Side-Effect Profile of LY354740: A Potent, Highly Selective, Orally Active Agonist for Group II Metabotropic Glutamate Receptors

David R. Helton, J P Tizzano, James A. Monn et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 282 citations

Benchmarking Safety Pharmacology regulatory packages and best practice

Silvana Lindgren, Alan Bass, Richard J. Briscoe et al. · Journal of Pharmacological and Toxicological Methods · 2008 · 107 citations

Drug Safety, Medicine, Pharmacovigilance +4

LY354740: a metabotropic glutamate receptor agonist which ameliorates symptoms of nicotine withdrawal in rats

David R. Helton, Joseph P. Tizzano, James A. Monn et al. · Neuropharmacology · 1997 · 103 citations

Molecular Pharmacology, Nicotine Withdrawal, Behavioral Neuroscience +10

2-Substituted (2<i>SR</i>)-2-Amino-2-((1<i>SR</i>,2<i>SR</i>)-2-carboxycycloprop-1-yl)glycines as Potent and Selective Antagonists of Group II Metabotropic Glutamate Receptors. 2. Effects of Aromatic Substitution, Pharmacological Characterization, and Bioavailability

Paul L. Ornstein, Thomas J. Bleisch, M. Brian Arnold et al. · Journal of Medicinal Chemistry · 1998 · 100 citations · Full text

Pharmacological Characterization, Synaptic Transmission, Pharmacotherapy +19