David V. Erbe

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

Carin C. Stamper, Yan Zhang, James F. Tobin et al. · Nature · 2001 · 477 citations

Crystal Structure, B7-1/ctla-4 Complex, Human Immune Responses +11

An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria

Abigail Liebow, Xingsheng Li, Timothy Racie et al. · Journal of the American Society of Nephrology · 2016 · 198 citations · Full text

Translational Medicine, Biochemistry, Primary Hyperoxaluria +15

Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors:  From the Active Site to the Second Phosphotyrosine Binding Site

Douglas Wilson, Zhao‐Kui Wan, Weixin Xu et al. · Journal of Medicinal Chemistry · 2007 · 156 citations · Full text

Proteinlipid Interaction, Drug Target, Molecular Biology +18

Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent

Dean R. Artis, Jack J. Lin, Chao Zhang et al. · Proceedings of the National Academy of Sciences · 2008 · 146 citations · Full text

Metabolic Syndrome, Medicinal Chemistry, Biochemistry +15

Molecular activation of PPARγ by angiotensin II type 1-receptor antagonists

David V. Erbe, Katherine Gartrell, Yanling Zhang et al. · Vascular Pharmacology · 2006 · 136 citations

Molecular Pharmacology, Signal Transduction, Molecular Physiology +11