The effect of smoking on chronic inflammation, immune function and blood cell composition

Ingrid Elisia, Vivian Lam, Brandon Cho, +8

Scientific Reports

Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination

Tadahito Yasuda, Mayu Koiwa, Atsuko Yonemura, +24

Cell Reports

Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer

Fumimasa Kitamura, Takashi Semba, Noriko Yasuda‐Yoshihara, +23

JCI Insight

Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer

Rumi Itoyama, Noriko Yasuda‐Yoshihara, Fumimasa Kitamura, +22

Cancer Letters

Tumor BiologyMetabolic ShiftPancreatic CancerBiochemistryMetabolic Reprogramming +10

Downregulation of 15‐hydroxyprostaglandin dehydrogenase by interleukin‐1β from activated macrophages leads to poor prognosis in pancreatic cancer

Kota Arima, Yoshihiro Komohara, Luke Bu, +13

Cancer Science

Transcriptional and Translational Dual-regulated Oncolytic Herpes Simplex Virus Type 1 for Targeting Prostate Tumors

Cleo Lee, Luke Bu, Arrigo DeBenedetti, +3

Molecular Therapy

UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells

Ismael Samudio, Katayoun Rezvani, Hila Shaim, +13

Blood

Effect of age on chronic inflammation and responsiveness to bacterial and viral challenges

Ingrid Elisia, Vivian Lam, Elyse Hofs, +8

PLoS ONE

Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk

Ingrid Elisia, Vivian Lam, Brandon Cho, +10

PLoS ONE

ImmunologyPathologyInnate ImmunityCancer Risk FactorsWhole Blood Samples +22

Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer

Lingfeng Fu, Atsuko Yonemura, Noriko Yasuda‐Yoshihara, +16

Gastric Cancer

Enhances Drug ResistanceMedicineCancer BiologyGastric CancerCell Biology +5