Rumi Itoyama

Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination

Tadahito Yasuda, Mayu Koiwa, Atsuko Yonemura et al. · Cell Reports · 2021 · 157 citations · Full text

Medicine, Cell Biology, Oncology +17

Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance

Tomoyuki Uchihara, Keisuke Miyake, Atsuko Yonemura et al. · Cancer Research · 2020 · 154 citations · Full text

Medicine, Cancer Biology, Oncology +17

Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer

Fumimasa Kitamura, Takashi Semba, Noriko Yasuda‐Yoshihara et al. · JCI Insight · 2023 · 96 citations · Full text

Medicine, Cancer Biology, Oncology +17

Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer

Rumi Itoyama, Noriko Yasuda‐Yoshihara, Fumimasa Kitamura et al. · Cancer Letters · 2021 · 64 citations · Full text

Medicine, Cancer Biology, Oncology +13

Downregulation of 15‐hydroxyprostaglandin dehydrogenase by interleukin‐1β from activated macrophages leads to poor prognosis in pancreatic cancer

Kota Arima, Yoshihiro Komohara, Luke Bu et al. · Cancer Science · 2017 · 51 citations · Full text

Medicine, Cancer Biology, Oncology +17