Bernárd P. Roques

Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB ₁ Receptor Knockout Mice

Catherine Ledent, Olga Valverde, G Cossu et al. · Science · 1999 · 3.6K citations

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene

Hans W. D. Matthes, Rafaël Maldonado, Frédéric Simonin et al. · Nature · 1996 · 1.7K citations

Molecular Pharmacology, µ-Opioid-receptor Gene, Pain Disorders +15

The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

Étienne Jacotot, L Ravagnan, Markus Loeffler et al. · The Journal of Experimental Medicine · 2000 · 446 citations · Full text

Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

Rafael Maldonado, Adolfo Saiardi, Olga Valverde et al. · Nature · 1997 · 439 citations

Addiction, Medicine, Opiate Rewarding Effects +9

Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding

K.S. Gajiwala, Hua Chen, Fabrice Cornille et al. · Nature · 2000 · 321 citations

Chromatin, Structural Bioinformatics, Winged-helix Protein Hrfx1 +7