Fiona S. Lucas

Inhibition of constitutive and inducible cyclooxygenase activity in human platelets and mononuclear cells by NSAIDS and Cox 2 inhibitors

Charles J. Grossman, Joanne Wiseman, Fiona S. Lucas et al. · Inflammation Research · 1995 · 125 citations

Inflammation, Thrombosis, Thrombopoiesis +12

Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors

J. Hamblin, Tony D. Angell, Stuart P. Ballantine et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 71 citations · Full text

Combinatorial Chemistry, Novel Structural Class, Biochemistry +6

GSK256066, an Exceptionally High-Affinity and Selective Inhibitor of Phosphodiesterase 4 Suitable for Administration by Inhalation: In Vitro, Kinetic, and In Vivo Characterization

Cathy Tralau-Stewart, Richard A. Williamson, Anthony T. Nials et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 69 citations

Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administration

Michael D. Woodrow, Stuart P. Ballantine, Michael D. Barker et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 56 citations

Molecular Pharmacology, Medicinal Chemistry, Novel Structural Class +11

Pyrazolopyridines as potent PDE4B inhibitors: 5-Heterocycle SAR

Charlotte Mitchell, Stuart P. Ballantine, Diane M. Coe et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 39 citations

Medicine, Anti-cancer Agent, Drug Development +3