Robert L. Simmons

In situ assembly of enzyme inhibitors using extended tethering

Daniel A. Erlanson, Joni W. Lam, Christian Wiesmann et al. · Nature Biotechnology · 2003 · 200 citations

Life Sciences, Biochemistry, Molecular Biology +14

Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery

Daniel A. Erlanson, Joseph W. Arndt, Mark T. Cancilla et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 85 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Pharmacokinetic Studies of Florfenicol in Koi Carp and Threespot Gourami <i>Trichogaster trichopterus</i> after Oral and Intramuscular Treatment

Roy P. Yanong, Eric W. Curtis, Robert L. Simmons et al. · Journal of Aquatic Animal Health · 2005 · 80 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

Identification of <i>N</i>-(4-((1<i>R</i>,3<i>S</i>,5<i>S</i>)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies

Matthew T. Burger, Gisele Nishiguchi, Wooseok Han et al. · Journal of Medicinal Chemistry · 2015 · 76 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae – Identification of LYS228

Folkert Reck, Alun Bermingham, Johanne Blais et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 58 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +13