Ram M. Thushara

A dietary colorant crocin mitigates arthritis and associated secondary complications by modulating cartilage deteriorating enzymes, inflammatory mediators and antioxidant status

Mahadevappa Hemshekhar, M. Sebastin Santhosh, K. Sunitha et al. · Biochimie · 2012 · 89 citations

Inflammation, Rheumatology, Rheumatoid Disorder +15

Melatonin elevates apoptosis in human platelets via ROS mediated mitochondrial damage

Kesturu S. Girish, Manoj Paul, Ram M. Thushara et al. · Biochemical and Biophysical Research Communications · 2013 · 74 citations

Inflammation, Mitophagy, Human Platelets +10

Unconjugated Bilirubin exerts Pro-Apoptotic Effect on Platelets via p38-MAPK activation

Somanathapura K. NaveenKumar, Ram M. Thushara, Mahalingam S. Sundaram et al. · Scientific Reports · 2015 · 71 citations · Full text

Crocin, a dietary additive protects platelets from oxidative stress-induced apoptosis and inhibits platelet aggregation

Ram M. Thushara, Mahadevappa Hemshekhar, M. Sebastin Santhosh et al. · Molecular and Cellular Biochemistry · 2012 · 70 citations

Inflammation, Thrombosis, Thrombopoiesis +12

Methotrexate Promotes Platelet Apoptosis via JNK-Mediated Mitochondrial Damage: Alleviation by N-Acetylcysteine and N-Acetylcysteine Amide

Manoj Paul, Mahadevappa Hemshekhar, Ram M. Thushara et al. · PLoS ONE · 2015 · 70 citations · Full text

Lipid Peroxidation, Apoptosis, Cell Death +20