Hongtu Zhao

Structure-based cleavage mechanism of <i>Thermus thermophilus</i> Argonaute DNA guide strand-mediated DNA target cleavage

Gang Sheng, Hongtu Zhao, Jiuyu Wang et al. · Proceedings of the National Academy of Sciences · 2013 · 270 citations · Full text

Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems

Jiuyu Wang, Jiazhi Li, Hongtu Zhao et al. · Cell · 2015 · 260 citations · Full text

Engineering, Crispr-cas Systems, Mechanistic Basis +10

Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli

Hongtu Zhao, Gang Sheng, Jiuyu Wang et al. · Nature · 2014 · 176 citations

Crystal Structure, Structural Bioinformatics, Protein X-ray Crystallography +5

Autonomous Generation and Loading of DNA Guides by Bacterial Argonaute

Daan C. Swarts, Malwina Szczepaniak, Gang Sheng et al. · Molecular Cell · 2017 · 146 citations · Full text

Dna Nanotechnology, Engineering, Biotechnology +10

Structural insights into the regulation of human serine palmitoyltransferase complexes

Yingdi Wang, Yiming Niu, Zhe Zhang et al. · Nature Structural & Molecular Biology · 2021 · 98 citations · Full text

Protein Function, Protein Expression, Biochemistry +6