Joseph Alvarado

Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CL^pro)

Sang Hoon Han, Christopher M. Goins, T. Arya et al. · Journal of Medicinal Chemistry · 2021 · 135 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity

Erin R. Aho, Jing Wang, Rocco D. Gogliotti et al. · Cell Reports · 2019 · 123 citations · Full text

Life Sciences, Molecular Biology, Oncology +10

Nickel, Manganese, Cobalt, and Iron-Catalyzed Deprotonative Arene Dimerization

Thanh Truong, Joseph Alvarado, Ly D. Tran et al. · Organic Letters · 2010 · 104 citations · Full text

Natural Sciences, Chemistry, Catalysis +13

Lithium Enolates in the Enantioselective Construction of Tetrasubstituted Carbon Centers with Chiral Lithium Amides as Noncovalent Stereodirecting Auxiliaries

Kai Yu, Ping Lu, Jeffrey J. Jackson et al. · Journal of the American Chemical Society · 2016 · 79 citations · Full text

Natural Sciences, Chemistry, Catalysis +9

Discovery of Potent 2-Aryl-6,7-dihydro-5 <i>H</i> -pyrrolo[1,2- <i>a</i> ]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design

Feng Wang, Kyu Ok Jeon, James M. Salovich et al. · Journal of Medicinal Chemistry · 2018 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17