Concepedia

Paul A. Negulescu

PA

37

Publications

6.7K

Citations

30

H-Index

1986

Active since

Affiliations

Vertex Pharmaceuticals (United States)(Current)

University of California, Berkeley

University of California, Irvine

Jean Brown Research

UC San Diego Health System

Paul A. Negulescu is an author at Vertex Pharmaceuticals (United States) specializing in medicine, cell biology, and cellular physiology.

Top concepts

Publications per year

1986–2025

37

Publications

37

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

Fredrick Van Goor, Sabine Hadidaꝉ, Peter D. J. Grootenhuis et al. · Proceedings of the National Academy of Sciences · 2009 · 1.2K citations · Full text

, , +15

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

Fredrick Van Goor, Sabine Hadidaꝉ, Peter D. J. Grootenhuis et al. · Proceedings of the National Academy of Sciences · 2011 · 1.1K citations · Full text

Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter

Gregor Zlokarnik, Paul A. Negulescu, Thomas E. Knapp et al. · Science · 1998 · 691 citations

Rescue of ΔF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules

Fredrick Van Goor, Kimberly Straley, Dong Cao et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2006 · 495 citations

A genetically encoded, fluorescent indicator for cyclic AMP in living cells

Manuela Zaccolo, Francesca De Giorgi, Charles Y. Cho et al. · Nature Cell Biology · 1999 · 479 citations

, , +10

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