Kimberly Straley

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

Fredrick Van Goor, Sabine Hadidaꝉ, Peter D. J. Grootenhuis et al. · Proceedings of the National Academy of Sciences · 2011 · 1.1K citations · Full text

Medicine, Molecular Biology, Pharmacology +13

Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation

Fang Wang, Jeremy Travins, Byron DeLaBarre et al. · Science · 2013 · 797 citations

Medicine, Cancer Biology, Oncology +10

Frequent Mutation of Isocitrate Dehydrogenase<i>(IDH)1</i>and<i>IDH2</i>in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping

Darrell R. Borger, Kenneth K. Tanabe, Kenneth C. Fan et al. · The Oncologist · 2011 · 722 citations · Full text

Medicine, Genetics, Oncology +17

Rescue of ΔF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules

Fredrick Van Goor, Kimberly Straley, Dong Cao et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2006 · 502 citations

Life Sciences, Cell Biology, Molecular Biology +17

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

Supriya K. Saha, Christine A. Parachoniak, Krishna S. Ghanta et al. · Nature · 2014 · 469 citations

Medicine, Cancer Biology, Molecular Biology +14