Zhaowu Xu

Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains

Terry D. Crawford, Vickie Tsui, E. Megan Flynn et al. · Journal of Medicinal Chemistry · 2016 · 117 citations · Full text

Molecular Biology, Chemical Biology, Pharmaceutical Chemistry +17

Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)

Alexander M. Taylor, Alexandre Côté, Michael C. Hewitt et al. · ACS Medicinal Chemistry Letters · 2016 · 111 citations · Full text

Drug Target, Chemical Biology, Cancer Biology +16

Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300

Terry D. Crawford, F. Anthony Romero, Kwong Wah Lai et al. · Journal of Medicinal Chemistry · 2016 · 94 citations · Full text

Synthesis and properties of iridium complexes based 1,3,4-oxadiazoles derivatives

Zhaowu Xu, Li Yang, Xuemei Ma et al. · Tetrahedron · 2007 · 65 citations

Inorganic Chemistry, Iridium Complexes, Coordination Complex +3

Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group

Gregory L. Hamilton, Huifen Chen, Gauri Deshmukh et al. · Bioorganic & Medicinal Chemistry Letters · 2019 · 36 citations · Full text

Pocket Group, Receptor-interacting Protein, Drug Target +10