Kathryn Houseman

Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere

Daniel P. Getman, Gary DeCrescenzo, R. Heintz et al. · Journal of Medicinal Chemistry · 1993 · 179 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes

Daniel H. Rich, Chong Qing Sun, J. V. N. Vara Prasad et al. · Journal of Medicinal Chemistry · 1991 · 126 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease

Srinivasan Nagarajan, Gary A. De Crescenzo, Daniel P. Getman et al. · Bioorganic & Medicinal Chemistry · 2003 · 96 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Inhibitors of HIV-1 Protease Containing the Novel and Potent (R)-(Hydroxyethyl)sulfonamide Isostere

Michael L. Vazquez, Martin L. Bryant, Michael Clare et al. · Journal of Medicinal Chemistry · 1995 · 48 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Optimization of Chromone-2-carboxamide Melanin Concentrating Hormone Receptor 1 Antagonists:  Assessment of Potency, Efficacy, and Cardiovascular Safety

Jennifer C. Freeman, Andrew S. Judd, Rajesh Iyengar et al. · Journal of Medicinal Chemistry · 2006 · 48 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13