I. Gardner

Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae

W. Alderton, Stéphane Berghmans, Paul Butler et al. · Xenobiotica · 2010 · 110 citations

Medicine, Pharmacology, Toxicology +17

A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease–Drug Interactions: Suppression of CYP3A by IL-6

Krishna K. Machavaram, Lisa M. Almond, Amin Rostami‐Hodjegan et al. · Clinical Pharmacology & Therapeutics · 2013 · 108 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Development of a Multicompartment Permeability‐Limited Lung PBPK Model and Its Application in Predicting Pulmonary Pharmacokinetics of Antituberculosis Drugs

Lu Gaohua, J. R. Wedagedera, Lisa M. Almond et al. · CPT Pharmacometrics & Systems Pharmacology · 2015 · 84 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of <b> <i>in silico</i> </b> physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man

Gill Allan, John D. Davis, Maurice Dickins et al. · Xenobiotica · 2008 · 61 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

VIVD: Virtual in vitro distribution model for the mechanistic prediction of intracellular concentrations of chemicals in in vitro toxicity assays

Ciarán Fisher, Ségolène Siméon, Masoud Jamei et al. · Toxicology in Vitro · 2018 · 61 citations · Full text

Pharmacy, Cell Biology, Toxicology +12