Krishna K. Machavaram

A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease–Drug Interactions: Suppression of CYP3A by IL-6

Krishna K. Machavaram, Lisa M. Almond, Amin Rostami‐Hodjegan et al. · Clinical Pharmacology & Therapeutics · 2013 · 107 citations

Cytokine Levels, Immunology, Physiologically-based Pharmacokinetic Modeling +20

Lymphatic Absorption of Subcutaneously Administered Proteins: Influence of Different Injection Sites on the Absorption of Darbepoetin Alfa Using a Sheep Model

Jagannath Kota, Krishna K. Machavaram, Danielle N McLennan et al. · Drug Metabolism and Disposition · 2007 · 67 citations

Prediction of the Pharmacokinetics, Pharmacodynamics, and Efficacy of a Monoclonal Antibody, Using a Physiologically Based Pharmacokinetic FcRn Model

Manoranjenni Chetty, Linzhong Li, Rachel H. Rose et al. · Frontiers in Immunology · 2015 · 35 citations · Full text

Immunology, Pharmacotherapy, Immunotherapy +18

Effect of Ketoconazole and Rifampicin on the Pharmacokinetics of Ranitidine in Healthy Human Volunteers: A Possible Role of P-Glycoprotein

Krishna K. Machavaram, Jayasagar Gundu, Madhusudan Rao Yamsani · Drug metabolism and drug interactions · 2006 · 26 citations

Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations

Krishna K. Machavaram, Chihiro Endo-Tsukude, Kimio Terao et al. · The AAPS Journal · 2019 · 25 citations

Inflammation, Different Ethnic Populations, Various Cyp450 Substrates +10