Johanna E. Welch

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

Paulina Kucharzewska, Helena C. Christianson, Johanna E. Welch et al. · Proceedings of the National Academy of Sciences · 2013 · 925 citations · Full text

Biological Microenvironments, Extracellular Microvesicles, Cancer Biology +17

ScFv Antibody-induced Translocation of Cell-surface Heparan Sulfate Proteoglycan to Endocytic Vesicles

Anders Wittrup, Sihe Zhang, Gerdy B. ten Dam et al. · Journal of Biological Chemistry · 2009 · 58 citations · Full text

Immunology, Viral Structural Protein, Immunotherapy +17

Hypoxia-Mediated Induction of the Polyamine System Provides Opportunities for Tumor Growth Inhibition by Combined Targeting of Vascular Endothelial Growth Factor and Ornithine Decarboxylase

Katrin J. Svensson, Johanna E. Welch, Paulina Kucharzewska et al. · Cancer Research · 2008 · 50 citations

The polyamines regulate endothelial cell survival during hypoxic stress through PI3K/AKT and MCL-1

Paulina Kucharzewska, Johanna E. Welch, Katrin J. Svensson et al. · Biochemical and Biophysical Research Communications · 2009 · 42 citations

Inflammation, Reductive Stress, Hypoxic Stress +13

Single chain fragment anti-heparan sulfate antibody targets the polyamine transport system and attenuates polyamine-dependent cell proliferation

Mattias Belting, Toin van Kuppevelt, Anders Wittrup et al. · International Journal of Oncology · 2008 · 28 citations · Full text

Tumor Biology, Polyamine-dependent Cell Proliferation, Polyamine Transport System +12