Helena C. Christianson

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

Paulina Kucharzewska, Helena C. Christianson, Johanna E. Welch et al. · Proceedings of the National Academy of Sciences · 2013 · 925 citations · Full text

Biological Microenvironments, Extracellular Microvesicles, Cancer Biology +17

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

Helena C. Christianson, Katrin J. Svensson, Toin H. Van Kuppevelt et al. · Proceedings of the National Academy of Sciences · 2013 · 846 citations · Full text

Molecular Biology, Extracellular Microvesicles, Tumor Biology +18

Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

Katrin J. Svensson, Helena C. Christianson, Anders Wittrup et al. · Journal of Biological Chemistry · 2013 · 659 citations · Full text

Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells

Erika Bourseau-Guilmain, Julien A. Menard, Elisabet Lindqvist et al. · Nature Communications · 2016 · 299 citations · Full text

Immunology, Pathology, Cancer Biology +18

Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells

Katrin J. Svensson, Paulina Kucharzewska, Helena C. Christianson et al. · Proceedings of the National Academy of Sciences · 2011 · 282 citations