Irene Sola

Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents

Elisabet Viayna, Irene Sola, Manuela Bartolini et al. · Journal of Medicinal Chemistry · 2014 · 146 citations · Full text

Rhein Derivatives, Multitarget Biological Profiling, Synaptic Transmission +18

Huprine–Tacrine Heterodimers as Anti-Amyloidogenic Compounds of Potential Interest against Alzheimer’s and Prion Diseases

Carles Galdeano, Elisabet Viayna, Irene Sola et al. · Journal of Medicinal Chemistry · 2011 · 97 citations · Full text

Peptide Science, Prion Peptide, Huprine–tacrine Heterodimers +19

Novel Levetiracetam Derivatives That Are Effective against the Alzheimer-like Phenotype in Mice: Synthesis, in Vitro, ex Vivo, and in Vivo Efficacy Studies

Irene Sola, Ester Aso, Daniela Frattini et al. · Journal of Medicinal Chemistry · 2015 · 63 citations

Synaptic Transmission, Levetiracetam–huprine Hybrid 10, Amyloid Aggregation +25

Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity

Ornella Di Pietro, Esther Vicente‐García, Martin C. Taylor et al. · European Journal of Medicinal Chemistry · 2015 · 61 citations · Full text

Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors

Ornella Di Pietro, Nelson Alencar, Gerard Esteban et al. · Bioorganic & Medicinal Chemistry · 2016 · 30 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Bioorganic Chemistry +11